That could be a corrupt file causing that problem.
Assuming your using Steam here. Open Steam and go to your library. Right click on Train Fever and select “properties.” Select the tab titled “Local Files” and then click on the lowest option “Verify Integrity of Game Cache.”
That will compare your local files with the manifest to make sure your local files are exactly as they should be. If something is corrupt it will replace that file with the correct one from the server.
This works with all Steam games by the way.